GENERAL CATALOGUE
HJB97
HY-112429 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-112429
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Catalog No: HY-112429
CAS No: 2093391-24-1
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
HJB97 is a high-affinity BET inhibitor with Ki values of 0.9 nM BRD2 BD1 , 0.27 nM BRD2 BD2 , 0.18 nM BRD3 BD1 , 0.21 nM BRD3 BD2 , 0.5 nM BRD4 BD1 , and 1.0 nM BRD4 BD2 . HJB97 can serve as a ligand for target protein Ligands for Target Protein for PROTAC for the development of PROTAC BET degraders with antitumor activity. HJB97 can be used for the synthesis of BETd-260 HY-101519 .