GENERAL CATALOGUE
HK-2-IN-2
HY-168717 · 50 mg
MedChemExpress · Cat: HY-168717
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Manufacturer product page
medchemexpress.com/antitumor-agent-190.htmlCatalog No: HY-168717
CAS No: 3056278-80-6
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
HK2-IN-2 Compound 26 is a Hexokinase 2 inhibitor that demonstrates significant anti-tumor activity by targeting microtubules and Hexokinase 2, with an IC50 value of 0.764 ?M against MD-MBA-231 cells. HK2-IN-2 effectively inhibits the activity of Hexokinase 2, leading to the accumulation of Reactive Oxygen Species and dysfunction of the mitochondrial membrane potential MMP , thereby promoting apoptosis and blocking the cell cycle.
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