GENERAL CATALOGUE
HKI-357 dimaleate
HY-103443A · 50 mg
MedChemExpress · Cat: HY-103443A
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medchemexpress.com/hki-357-dimaleate.html
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Catalog No: HY-103443A
CAS No: 915942-25-5
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress
Description
HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and ERBB2 with IC50s of 34 nM and 33 nM, respectively. HKI-357 dimaleate suppresses EGFR autophosphorylation at Y1068 , and AKT and MAPK phosphorylation.
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