GENERAL CATALOGUE
HKI-357
HY-103443 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-103443
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medchemexpress.com/hki-357.html
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Catalog No: HY-103443
CAS No: 848133-17-5
Category: JAK STAT Signaling
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 with IC50s of 34 nM and 33 nM, respectively. HKI-357 suppresses EGFR autophosphorylation at Y1068 , and AKT and MAPK phosphorylation.
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