GENERAL CATALOGUE
HL23
HY-155248 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-155248
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medchemexpress.com/hl23.html
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Catalog No: HY-155248
CAS No: 1448355-15-4
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
HL23 is a histone deacetylase HDAC inhibitor with activity against hepatocellular carcinoma HCC . HL23 enhances acetylation of the TXNIP promoter and upregulates TXNIP expression, thereby mediating potassium channel activity and triggering TXNIP-dependent potassium deprivation. HL23 inhibits HCC progression and metastasis and has a synergistic effect with Sorafenib HY-10201 and is more potent than Sorafenib+Vorinostat HY-10221 .
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