GENERAL CATALOGUE
HL435
HY-161769 · 50 mg
MedChemExpress · Cat: HY-161769
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/hl435.html
Sponsored
Catalog No: HY-161769
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
HL435 is a heterobifunctional molecule that degrades BRD4 by linking to JQ1, with DC50 of 11.9 nM and 21.9 nM, in MDA-MB-231 and MCF-7 cells, respectively. HL435 inhibits the proliferation of MDA-MB-231, MCF-7, 22Rv1 and A549, arrests the cell cycle and induces apoptosis. HL435 exhibits antitumor activity in mouse model. Pink: ligand for target protein JQ-1 HY-78695 ; Black: linker HY-W004640 ; blue: ligand for E3 ligase HL389 HY-161770
More from MedChemExpress
2-Bromohexadecanoic acid
HY-111770
Apoptosis
Uridine 5'-monophosphate-15N2
HY-101981S
Apoptosis
AZD-5991
HY-101533
Apoptosis
HDAC-IN-37
HY-146750
Apoptosis
Anti-inflammatory agent 47
HY-155568
Apoptosis
YLT205
HY-117515
Apoptosis
pan-HER-IN-2
HY-144677
Apoptosis
HDAC-IN-84
HY-170379
Apoptosis