HLA DMB (14D11) Rabbit Monoclonal Antibody

Description

EnkiLife offers the HLA DMB (14D11) Rabbit Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ICC/IF application. Alternative Names of Immunogen: DMB; RING7;. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:100-1:500 Background: HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. Plays a critical role in catalyzing the release of class II- associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.