HMG2 Mouse Monoclonal Antibody

Description

EnkiLife offers the HMG2 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB application. Alternative Names of Immunogen: High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:8000 Background: This gene encodes a protein that belongs to thenon-histone chromosomal high mobility group (HMG) protein family.HMG proteins function as architectural factors and are essentialcomponents of the enhancesome. This protein contains structuralDNA-binding domains and may act as a transcriptional regulatingfactor. Identification of the deletion, amplification, andrearrangement of this gene that are associated with myxoidliposarcoma suggests a role in adipogenesis and mesenchymaldifferentiation. A gene knock out study of the mouse counterpartdemonstrated that this gene is involved in diet-induced obesity.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized.