HN1 Rabbit Monoclonal Antibody

Description

EnkiLife offers the HN1 Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,ICC,FC application. Alternative Names of Immunogen: ARM2; HN1; HN1A;;JPT1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100 Background: Modulates negatively AKT-mediated GSK3B signaling.Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions.