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HPK1-IN-57
GENERAL CATALOGUE

HPK1-IN-57

HY-172594 · 50 mg

MedChemExpress · Cat: HY-172594

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medchemexpress.com/hpk1-in-57.html
Catalog No: HY-172594
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

HPK1-IN-57 Compound 10c is a hematopoietic progenitor kinase 1 HPK1 inhibitor with an IC50 value of 0.09 nM. HPK1-IN-57 inhibits the activity of HPK1 kinase, hindering the phosphorylation of the downstream adaptor protein SLP76 IC50 is 33.74 nM and effectively stimulating the secretion of the T cell activation marker IL-2 EC50 is 84.24 nM . HPK1-IN-57 is promising for research of tumor immunotherapy.

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