HPK1 Rabbit Polyclonal Antibody

Description

EnkiLife offers the HPK1 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: MAP4K1; HPK1; Mitogen-activated protein kinase kinase kinase kinase 1; Hematopoietic progenitor kinase; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:500,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000 Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein. cofactor:Magnesium. function:May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. similarity:Contains 1 CNH domain. similarity:Contains 1 protein kinase domain. subunit:Interacts with MAP3K1. tissue specificity:Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine. Research Area:MAPK_ERK_Growth;MAPK_G_Protein;