GENERAL CATALOGUE
HPO-DAEE
HY-158205 · 50 mg
MedChemExpress · Cat: HY-158205
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Catalog No: HY-158205
CAS No: 1895934-61-8
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
HPO-DAEE 4-Hydroperoxy-2-decenoic acid ethyl ester elicits nuclear accumulation of Nrf2 and activated antioxidant response element ARE . HPO-DAEE induces antioxidant genes upregulation eg: HO-1 through Nrf2-ARE signaling. HPO-DAEE induces reactive oxygen species generation. HPO-DAEE also inhibits histone deacetylase and upregulate expression of extracellular superoxide dismutase via histone acetylation. HPO-DAEE protects against 6-hydroxydopamine-induced cell death via activation of Nrf2-ARE and eIF2?-ATF4 pathways.
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