GENERAL CATALOGUE
HPOB
HY-19747 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-19747
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Catalog No: HY-19747
CAS No: 1429651-50-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
HPOB is a highly potent and selective inhibitor of HDAC6 with an IC50 of 56 nM. HPOB displays >30 fold less potent against other HDACs. HPOB enhances the effectiveness of DNA-damaging anticancer agents in transformed cells but not normal cells. HPOB does not block the ubiquitin-binding activity of HDAC6.
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