GENERAL CATALOGUE
HQY1428
HY-172970 · 50 mg
MedChemExpress · Cat: HY-172970
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Manufacturer product page
medchemexpress.com/hqy1428.htmlCatalog No: HY-172970
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
HQY1428 is an orally active CDK12 inhibitor. HQY1428 inhibits DNA replication, causes G2/M arrest in SKOV3 cells, induces DNA double-strand breaks and apoptosis. HQY1428 has anti-tumor activity in the SKOV3 xenograft mouse model. HQY1428 combined with the HER2 inhibitor Lapatinib HY-50898 in the NCI-N87 xenograft mouse model produces a synergistic therapeutic effect.
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