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HS-276
GENERAL CATALOGUE

HS-276

HY-147141 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-147141

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medchemexpress.com/hs-276.html
Catalog No: HY-147141
CAS No: 2767422-72-8
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

HS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKK?-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 can be used for rheumatoid arthritis RA research.

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