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hsa-miR-8077 antagomir
GENERAL CATALOGUE

hsa-miR-8077 antagomir

HY-RI02469A · 5 nmol

MedChemExpress · Cat: HY-RI02469A

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Catalog No: HY-RI02469A
Category: Epigenetics
Pack Size: 5 nmol
Brand: MedChemExpress

Description

hsa-miR-8077 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5 end, 4 phosphorothioates at the 3 end, 1 cholesterol group at the 3 end, and full-length nucleotide 2-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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