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Hsp90-Cdc37-IN-2
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Hsp90-Cdc37-IN-2

HY-130624 · 1 mg

MedChemExpress · Cat: HY-130624

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Catalog No: HY-130624
CAS No: 2413849-81-5
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress

Description

Hsp90-Cdc37-IN-2 Compound 41 is an inhibitor for the interaction between heat shock protein 90 Hsp90 and cyclin 37 Cdc37 . Hsp90-Cdc37-IN-2 inhibits the proliferation of cancer cell A549, MCF-7, HOS and HepG2 with IC50 of 0.41-0.94 ?M. Hsp90-Cdc37-IN-2 decreases the mitochondrial membrane potential, induces apoptosis, and arrest cell cycle at G0/G1 phase in A549.

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