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hSTING activator-1
GENERAL CATALOGUE

hSTING activator-1

HY-173399 · 50 mg

MedChemExpress · Cat: HY-173399

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Catalog No: HY-173399
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

hSTING activator-1 Compound 68 is a STING agonist. hSTING activator-1 can effectively activate multiple human STING variants R232, H232, HAQ with EC50 values of 56 nM, 89 nM and 51 nM, respectively. hSTING activator-1 activates the type I interferon pathway by directly binding to STING protein and stabilizing its conformation, promoting downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 inhibits fibrosarcoma tumor growth and has potential in cancer research.

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