Human CCL5 mRNA

Description

Human CCL5 mRNA encodes the human C-C motif chemokine ligand 5 CCL5 protein, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. CCL5 is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine C-C motif receptor 5 CCR5 , and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor.