Human CXCR2 mRNA

Description

Human CXCR2 mRNA encodes the human C-X-C motif chemokine receptor 2 CXCR2 protein, a member of the G-protein-coupled receptor family. CXCR2 is a receptor for interleukin 8 IL8 . It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine C-X-C motif ligand 1 CXCL1/MGSA , a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth.