Human IFNAR1 CRISPR Knockout A549 Stable Cell Line

Description

This cell line has been modified using CRISPR/Cas9 technology to knock out the IFNAR1 gene, which encodes the interferon-alpha/beta receptor alpha chain. The absence of IFNAR1 disrupts the interferon signaling pathway, making this cell line a valuable tool for studying the mechanisms of immune response, viral infection, and cytokine signaling. Applications of this stable cell line include research in immunology, virology, and drug discovery, particularly in the development and testing of antiviral therapies and immune-modulating agents. Complete list of cell lines from this panel: Cat. T3517 - Human IFNAR1 CRISPR Knockout A549 Stable Cell Line Cat. T3518 - Human IFNLR1 CRISPR Knockout A549 Stable Cell Line Cat. T3519 - Human IFNAR1-IFNLR1 CRISPR Knockout A549 Stable Cell Line