Human TLR5 mRNA

Description

Human TLR5 mRNA encodes the human toll like receptor 5 TLR5 protein, a member of the Toll-like receptor TLR family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR5 recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes.