GENERAL CATALOGUE
HXR9 hydrochloride
HY-P3245A · 1 mg
MedChemExpress · Cat: HY-P3245A
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Catalog No: HY-P3245A
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
HXR9 hydrochloride is a cell-permeable peptide and a competitive antagonist of HOX/PBX interaction. HXR9 hydrochloride antagonizes the interaction between HOX and a second transcrip-tion factor PBX , which binds to HOX proteins in paralogue groups1 to 8. HXR9 hydrochloride selectively decreases cell proliferation and promotes apoptosis in cells with a high level of expression of the HOXA/PBX3 genes, such as MLL-rearranged leukemic cells.
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