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?-Hydroxyisovalerylshikonin
GENERAL CATALOGUE

?-Hydroxyisovalerylshikonin

HY-N4201 · 1 mg

MedChemExpress · Cat: HY-N4201

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Catalog No: HY-N4201
CAS No: 7415-78-3
Category: JAK STAT Signaling
Pack Size: 1 mg
Brand: MedChemExpress

Description

Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermum erythrorhizon, acts as a potent inhibitor of protein tyrosine kinases PTK , with IC50s of 0.7?M and 1?M for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells.

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