GENERAL CATALOGUE
Hyp-dBET1
HY-173256 · 50 mg
MedChemExpress · Cat: HY-173256
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medchemexpress.com/hyp-dbet1.html
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Catalog No: HY-173256
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
Hyp-dBET1 is a PROTAC degrader targeting BRD4. Hyp-dBET1 has an IC50 value of 3.4 ?M in MDA-MB-231 cells. Hyp-dBET1 can be activated by hypoxia and recruit the E3 ubiquitin ligase and degrade BRD4 through ubiquitin-proteasome system. Hyp-dBET1 can be used for anti-tumor study.
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