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Hypidone hydrochloride
GENERAL CATALOGUE

Hypidone hydrochloride

HY-100769 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-100769

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Catalog No: HY-100769
CAS No: 1339058-04-6
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Hypidone hydrochloride YL0919 is an orally active antidepressant agent with dual activity as a highly seletive 5-HT uptake blocker and an effective 5-HT1A receptor agonist Ki=0.19 nM . Hypidone hydrochloride inhibits the uptake of 3H -5-HT into rat cerebral cortical synaptosomes and HEK293 cells with IC50s of 1.78 nM and 1.93 nM, respectively. Hypidone hydrochloride shows remarkable antidepressant effects in animal models and has the poential for the investigation of depressive disorder.

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