GENERAL CATALOGUE
Hyrtiosal
HY-N15327 · 50 mg
MedChemExpress · Cat: HY-N15327
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Catalog No: HY-N15327
CAS No: 138355-07-4
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Hyrtiosal, found in the marine sponge Hyrtios erectus, is an inhibitor of the N-terminal domain NTD of HIV-1 integrase HIV-1 IN with an IC50 value of 9.60-0.86 ?M. Hyrtiosal binds to the Ser17, Trp19, and Lys34 sites on the NTD of HIV-1 IN, inhibiting the binding of HIV-1 viral DNA to integrase and interfering with the formation of the pre-integrated complex of HIV-1. Hyrtiosal is promising for research of anti-HIV agents.
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