GENERAL CATALOGUE
HZX-02-059
HY-112440 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-112440
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medchemexpress.com/Methuosis_inducer_1.html
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Catalog No: HY-112440
CAS No: 2240205-30-3
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
HZX-02-059 is a potent methuosis inducer and dual-target PIKfyve/tubulin inhibitor with anticancer activity. Methuosis mainly disrupts the balance of endocytosis and exocytosis, forming a large number of vesicles and inducing cell death. HZX-02-059 also induces cell vacuolization, promotes apoptosis, downregulates the p53 pathway, inhibits PI3K/AKT phosphorylation, and inhibits c-Myc and NF-?B transcription.
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