GENERAL CATALOGUE
I3IN-002
HY-174228 · 5 mg
MedChemExpress · Cat: HY-174228
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medchemexpress.com/i3in-002.htmlCatalog No: HY-174228
CAS No: 552829-57-9
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
I3IN-002 is a small-molecule RNA-binding protein IGF2BP3 inhibitor with an IC50 value of approximately 2 ?M in SEM cells. I3IN-002 interferes with interaction with m6 A-modified mRNAs, disrupting the stabilization of target genes such as CDK6, MYC, and BCL2 to inhibit leukemic cell growth, induce cell cycle arrest, and promote apoptosis. I3IN-002 is promising for research of B-cell acute lymphoblastic leukemia.
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