GENERAL CATALOGUE
IACS-13909
HY-137092 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-137092
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Manufacturer product page
medchemexpress.com/iacs-13909.htmlCatalog No: HY-137092
CAS No: 2160546-07-4
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
IACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM. IACS-13909 is more selective for SHP2 than other phosphatases including SHP1 . IACS-13909 has antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinases RTK -dependent cancers.
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