Ibandronate Sodium

Description

Ibandronate Sodium is an orally active, selective inhibitor of farnesyl pyrophosphate synthase FPP synthase . Ibandronate Sodium can block the mevalonate pathway to inhibit the isoprenylation modification of small GTPases such as RAS, RHO family proteins , induce tumor cell apoptosis and inhibit bone resorption. Ibandronate Sodium inhibits tumor cell proliferation such as ER+ breast cancer cells , promotes the expression of the pro-apoptotic gene FAS, and can produce synergistic anti-tumor effects with anti-estrogen compounds. Ibandronate Sodium is used in the study of osteoporosis and bone metastatic tumors such as breast cancer bone metastasis .