Ibandronate Sodium Monohydrate

Description

Ibandronate Sodium Monohydrate BM-210955; RPR-102289A is an orally active, selective inhibitor of farnesyl pyrophosphate synthase FPP synthase . Ibandronate Sodium Monohydrate can block the mevalonate pathway to inhibit the isoprenylation modification of small GTPases such as RAS, RHO family proteins , induce tumor cell apoptosis and inhibit bone resorption. Ibandronate Sodium Monohydrate inhibits tumor cell proliferation such as ER+ breast cancer cells , promotes the expression of the pro-apoptotic gene FAS, and can produce synergistic anti-tumor effects with anti-estrogen compounds. Ibandronate Sodium Monohydrate is used in the study of osteoporosis and bone metastatic tumors such as breast cancer bone metastasis .