GENERAL CATALOGUE
IC 86621
HY-100707 · 5 mg
MedChemExpress · Cat: HY-100707
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medchemexpress.com/ic-86621.htmlCatalog No: HY-100707
CAS No: 404009-40-1
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
IC 86621 is a potent DNA-dependent protein kinase DNA-PK inhibitor, with an IC50 of 120 nM. IC 86621 also acts as a selective and reversible ATP-competitive inhibitor.IC 86621 inhibits DNA-PK mediated cellular DNA double-strand break DSB repair EC50=68 AAasAasAAmuM . IC 86621 increases DSB-induced antitumor activity without cytotoxic effects. IC 86621 can protects rheumatoid arthritis RA T cells from apoptosis.