GENERAL CATALOGUE
ICMT-IN-48
HY-157116 · 50 mg
MedChemExpress · Cat: HY-157116
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Catalog No: HY-157116
CAS No: 337486-54-1
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
ICMT-IN-48 compound 1 is an ICMT inhibitor that is competitive Km=13 ?M for the prenylated methyl acceptor, the first substrate of ICMT. ICMT-IN-48 inhibits ICMT activity with IC50s affected by the concentration of the second substrate S-adenosylmethinine SAM , and the IC50s are 3.5 ?M 1AAAasAaKm SAM and 2.3 ?M 10AAAasAaKm SAM , respectively.
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