Idebenone (Standard)

Description

Idebenone Standard is the analytical standard of Idebenone. This product is intended for research and analytical applications. Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimers disease, Huntingtons disease. Idebenone oxidised form has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates IC50=16.65 ?M . Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. Idebenone quickly crosses the blood-brain barrier.