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IDH-305
GENERAL CATALOGUE

IDH-305

HY-104036 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-104036

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medchemexpress.com/IDH-305.html
Catalog No: HY-104036
CAS No: 1628805-46-8
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor that targets IDH1 R132 mutation. IDH-305 exhibits greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT IC50= 27 nM IDH1R132H , 28 nM IDH1R132C , 6.14 AAasAasAAmuM IDH1WT .

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