GENERAL CATALOGUE
IDH1 Inhibitor 2
HY-128661 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-128661
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medchemexpress.com/idh1-inhibitor-2.htmlCatalog No: HY-128661
CAS No: 2244895-42-7
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
IDH1 Inhibitor 2 compound 13 is a potent wild-type IDH1 inhibitor that exerts its activity through covalent modification of His315 with an IC50 value of 110 nM. IDH1 Inhibitor 2 can dose-dependently reduce the intracellular reduced glutamine metabolic flux, thereby affecting cellular metabolic homeostasis. IDH1 Inhibitor 2 can be used to study the role of IDH1 in cellular metabolic regulation and cancer development.
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