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IDH2R140Q-IN-2
GENERAL CATALOGUE

IDH2R140Q-IN-2

HY-156158 · 1 mg

MedChemExpress · Cat: HY-156158

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Catalog No: HY-156158
CAS No: 2749568-16-7
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress

Description

IDH2R140Q-IN-2 compound 36 is an an orally active IDH2R140Q inhibitor IC50: 29 nM . IDH2R140Q-IN-2 reduces D2HG production in TF-1 cell lines expressing mutant IDH2R140Q IC50: 10 nM . IDH2R140Q-IN-2 suppresses D2HG levels in tumor tissue. IDH2R140Q-IN-2 can be used for research of acute myeloid leukemia AML .

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