Ifenprodil tartrate

Description

Ifenprodil NP-120 tartrate, a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors IC50=0.34 ?M over 400-fold than at NR1A/NR2A receptors IC50=146 ?M . Ifenprodil tartrate is an ?1 adrenergic receptor antagonist. Ifenprodil tartrate inhibits GIRK Kir3 , reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has reliable inhibitory effects against A/H1N1 strains EC50 of 6.6 AAasAasAAmuM . Ifenprodil tartrate has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil tartrate can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease.