GENERAL CATALOGUE
iFSP1
HY-136057 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-136057
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Catalog No: HY-136057
CAS No: 150651-39-1
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
iFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 FSP1 AIFM2 with an EC50 of 103 nM. iFSP1 selectively induces ferroptosis in GPX4-knockout cells which overexpressed FSP1. iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as 1S,3R -RSL3 HY-100218A .
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