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IGF1R Stable Ba/F3 Cell Line
GENERAL CATALOGUE

IGF1R Stable Ba/F3 Cell Line

T3073 · 1 x 106 cells / 1.0 mL

abm good · Cat: T3073

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Catalog No: T3073
Category: Cellular Materials
Pack Size: 1 x 106 cells / 1.0 mL
Brand: abm good

Description

Fusing a kinase domain to a homodimerization domain such as the PNT domain of ETV6 can result in activated kinase. The IGF1R Stable Ba/F3 Cell Line expresses activated human IGF1R tyrosine kinase that is linked to a GFP reporter GFP-ETV6-IGF1R in MSCV-puro vector . Ba/F3 cells expressing activated tyrosine kinase become completely dependent on the kinase activity for survival and as a result, the cells can be propagated even in the absence of IL-3.

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