IL-2 Mouse Monoclonal Antibody

Description

EnkiLife offers the IL-2 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,ICC,ELISA application. Alternative Names of Immunogen: Aldesleukin; TCGF; interleukin-2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000 Background: IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. Research Area: TGF-beta signaling pathway,PI3K-Akt signaling pathway