GENERAL CATALOGUE
IL-6-IN-2
HY-177063 · 5 mg
MedChemExpress · Cat: HY-177063
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Catalog No: HY-177063
CAS No: 296790-70-0
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
IL-6-IN-2 Compound 15 is an inhibitor of the IL-6/IL-6R protein interaction. The ?G binding energy of IL-6-IN-2 is ?36.50 kcal/mol. Contributions of Lys66, Phe74, Gln175, Ser176, and Arg179 to IL-6 binding are ?1.10, ?8.68, ?6.91, ?3.69, and ?1.72 kcal/mol, respectively. IL-6-IN-2 exhibits low gastrointestinal GI absorption.
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