IL1B Mouse Monoclonal Antibody

Description

EnkiLife offers the IL1B Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for IHC,ICC,ELISA,FC application. Alternative Names of Immunogen: IL-1; IL1F2; IL1beta; IL1-BETA. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1. This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase2 by this cytokine in the central nervous system is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Research Area: TGF-beta signaling pathway,MAPK signaling pathway