IL2RA Mouse Monoclonal Antibody

Description

EnkiLife offers the IL2RA Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Monkey,Rat species and is suitable for WB,IHC,ICC,ELISA application. Alternative Names of Immunogen: CD25; IL2R; TCGFR; IDDM10. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000 Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Research Area: TGF-beta signaling pathway,PI3K-Akt signaling pathway,Jak-STAT signaling pathway