IL3RA Mouse Monoclonal Antibody

Description

EnkiLife offers the IL3RA Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for ICC,ELISA,FC application. Alternative Names of Immunogen: IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. Research Area: TGF-beta signaling pathway,PI3K-Akt signaling pathway,Jak-STAT signaling pathway