

ab141046 ยท 5 g
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Description
MW 316.9 Da, Purity >98 %. Tricyclic antidepressant with various pharmacological activities. Inhibits reuptake inhibitors Ki values are 19, 98 and 1000 nM for SERT, NET and DAT, respectively. Muscarinic receptor inhibitor IC50 = 0.13 muM for M2 . Serotonin receptor inhibitor Ki values are 94 and 160 nM for 5-HT2A and 5-HT2C, respectively . Crosses the blood-brain barrier.






