Immortalized Mouse Retinal Pigmented Epithelial Cells - HPV16 E6/E7

Description

The Immortalized Mouse Retinal Pigmented Epithelial Cells- HPV E6/E7, derived from healthy C57B1/6 mouse RPE cells, is a cell line that retained many of their in vivo phenotypic characteristics. RPE-specific markers such as RPE65 and cellular retinaldehyde binding protein CRALBP , as well as epithelial markers ZO1, cytokeratin 8 and 18 are expressed in the Immortalized Mouse Retinal Pigmented Epithelial Cells- HPV E6/E7. These cells are useful in studies of RPE cell biology and investigation of ocular disease including age related macular degeneration AMD . Western Blot was used to verify the HPV protein expression in the immortalized cell line.