Immortalized MS-/- Mouse Alveolar Macrophage Cells (ZK2)

Description

Alveolar macrophages were isolated from the brochoalveolar lavage fluid of MARCO-/- SR-AI/II-/- MS-/- mice and were immortalized with the J2 retrovirus to establish the Immortalized MS-/- Mouse Alveolar Macrophage Cells ZK2 . ZK2 cells exhibit the macrophage morphology, functional activity, and the ability to bind to and ingest particles are reduced due to the deficiency in MARCO and SR-AI/II scavenger receptors. It is a valuable tool to study the functions of MARCO and SR-AI/II scavenger receptors and particle toxicity. abm also have available the ZK1 T0676 and ZK6 T0678 clones established from limiting dilution. PCR genotyping was used to determine the deficiency of MARCO and SR-AI/II.