GENERAL CATALOGUE
INCB086550
HY-134884 · 5 mg
MedChemExpress · Cat: HY-134884
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Catalog No: HY-134884
CAS No: 2230911-59-6
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
INCB086550 is a potent, oral, small-molecule PD-L1 inhibitor with IC50s value of 3.1, 4.9 and 1.9 nM for human, cynomolgus, and rat, respectively. INCB086550 promotes the dimerization of cell-surface PD-L1 and induces PD-L1 entry into Golgi vesicles then traffick to the nucleus. INCB086550 can be used for multiple cancers research.
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